Synthesis and anti-prion aggregation activity of acylthiosemicarbazide analogues

• Príomhchruthaitheoirí: Dong Hwan Kim (Údar), Jaehyeon Kim (Údar), Hakmin Lee (Údar), Dongyun Lee (Údar), So Myoung Im (Údar), Ye Eun Kim (Údar), Miryeong Yoo (Údar), Yong-Pil Cheon (Údar), Jason C. Bartz (Údar), Young-Jin Son (Údar), Eun-Kyoung Choi (Údar), Yong-Sun Kim (Údar), Jae-Ho Jeon (Údar), Hyo Shin Kim (Údar), Sungeun Lee (Údar), Chongsuk Ryou (Údar), Tae-gyu Nam (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Prions are infectious protein particles known to cause prion diseases. The biochemical entity of the pathogen is the misfolded prion protein (PrPSc) that forms insoluble amyloids to impair brain function. PrPSc interacts with the non-pathogenic, cellular prion protein (PrPC) and facilitates conversi...