Novel Two-Step Classifier for Torsades de Pointes Risk Stratification from Direct Features
While pre-clinical Torsades de Pointes (TdP) risk classifiers had initially been based on drug-induced block of hERG potassium channels, it is now well established that improved risk prediction can be achieved by considering block of non-hERG ion channels. The current multi-channel TdP classifiers c...
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Frontiers Media S.A.,
2017-11-01T00:00:00Z.
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