Risk evaluation of impurities in topical excipients: The acetol case

• Main Authors: Jente Boonen (Author), Lieselotte Veryser (Author), Lien Taevernier (Author), Nathalie Roche (Author), Kathelijne Peremans (Author), Christian Burvenich (Author), Bart De Spiegeleer (Author)
• Format: Book
• Published: Elsevier, 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pharmaceutical excipients for topical use may contain impurities, which are often neglected from a toxicity qualification viewpoint. The possible impurities in the most frequently used topical excipients were evaluated in-silico for their toxicity hazard. Acetol, an impurity likely present in differ...