Mechanisms of the Testis Toxicity Induced by Chronic Exposure to Mequindox

• Main Authors: Qianying Liu (Author), Zhixin Lei (Author), Anxiong Huang (Author), Qirong Lu (Author), Xu Wang (Author), Saeed Ahmed (Author), Ihsan Awais (Author), Zonghui Yuan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mequindox (MEQ) is a synthetic antimicrobial agent widely used in China since the 1980s. Although the toxicity of MEQ is well recognized, its testis toxicity has not been adequately investigated. In the present study, we provide evidence that MEQ triggers oxidative stress, mitochondrion dysfunction...