1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery

WaterLOGSY is a sensitive ligand-observed NMR experiment for detection of interaction between a ligand and a protein and is now well-established as a screening technique for fragment-based lead discovery. Here we develop and assess a protocol to derive ligand epitope mapping from WaterLOGSY data and...

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Bibliographic Details
Main Authors: Claire Raingeval (Author), Olivier Cala (Author), Béatrice Brion (Author), Marc Le Borgne (Author), Roderick Eliot Hubbard (Author), Isabelle Krimm (Author)
Format: Book
Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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