1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery
WaterLOGSY is a sensitive ligand-observed NMR experiment for detection of interaction between a ligand and a protein and is now well-established as a screening technique for fragment-based lead discovery. Here we develop and assess a protocol to derive ligand epitope mapping from WaterLOGSY data and...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
Taylor & Francis Group,
2019-01-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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