Overexpression of SP1 restores autophagy to alleviate acute renal injury induced by ischemia-reperfusion through the miR-205/PTEN/Akt pathway

Abstract Background Acute kidney injury (AKI) is a major kidney disease with poor clinical outcome. SP1, a well-known transcription factor, plays a critical role in AKI and subsequent kidney repair through the regulation of various cell biologic processes. However, the underlying mechanism of SP1 in...

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Main Authors: Chong Huang (Author), Yan Chen (Author), Bin Lai (Author), Yan-Xia Chen (Author), Cheng-Yun Xu (Author), Yuan-Fei Liu (Author)
Format: Book
Published: BMC, 2021-02-01T00:00:00Z.
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