Whole-body hypothermia in mild neonatal encephalopathy: protocol for a multicentre phase III randomised controlled trial

• Main Authors: Reema Garegrat (Author), Paolo Montaldo (Author), Constance Burgod (Author), Stuti Pant (Author), Munirah Mazlan (Author), Balamurugan Palanisami (Author), Ela Chakkarapani (Author), Kerry Woolfall (Author), Samantha Johnson (Author), Patricia Ellen Grant (Author), Sarah Land (Author), Mariam Mahmoud (Author), Tony Brady (Author), Victoria Cornelius (Author), Eleri Adams (Author), Jon Dorling (Author), Narendra Aladangadi (Author), Paul Fleming (Author), Ronit Pressler (Author), Andrew Shennan (Author), Stavros Petrou (Author), Aung Soe (Author), Paul Basset (Author), Seetha Shankaran (Author), Sudhin Thayyil (Author)
• Format: Book
• Published: BMC, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Mild hypoxic ischemic encephalopathy is associated with sub optimal cognition and learning difficulties at school age. Although whole-body hypothermia reduces death and disability after moderate or severe encephalopathy in high-income countries, the safety and efficacy of hypothe...