Causal linkage of tobacco smoking with ageing: Mendelian randomization analysis towards telomere attrition and sarcopenia

• Main Authors: Sehoon Park (Author), Seong Geun Kim (Author), Soojin Lee (Author), Yaerim Kim (Author), Semin Cho (Author), Kwangsoo Kim (Author), Yong Chul Kim (Author), Seung Seok Han (Author), Hajeong Lee (Author), Jung Pyo Lee (Author), Kwon Wook Joo (Author), Chun Soo Lim (Author), Yon Su Kim (Author), Dong Ki Kim (Author)
• Format: Book
• Published: Wiley, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Ageing traits and frailty are important health issues in modern medicine. Evidence supporting the causal effects of tobacco smoking on various ageing traits is required. Methods This study performed Mendelian randomization (MR) analysis instrumenting 377 genetic variants associat...