Intranasal Delivery of miR-146a Mimics Delayed Seizure Onset in the Lithium-Pilocarpine Mouse Model

• Main Authors: Hua Tao (Author), Jianghao Zhao (Author), Tingting Liu (Author), Yujie Cai (Author), Xu Zhou (Author), Huaijie Xing (Author), Yan Wang (Author), Mingkang Yin (Author), Wangtao Zhong (Author), Zhou Liu (Author), Keshen Li (Author), Bin Zhao (Author), Haihong Zhou (Author), Lili Cui (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Unveiling the key mechanism of temporal lobe epilepsy (TLE) for the development of novel treatments is of increasing interest, and anti-inflammatory miR-146a is now considered a promising molecular target for TLE. In the current study, a C57BL/6 TLE mouse model was established using the lithium-pilo...