Hepatocyte-targeting and microenvironmentally responsive glycolipid-like polymer micelles for gene therapy of hepatitis B

• Main Authors: Jing Miao (Author), Xiqin Yang (Author), Xuwei Shang (Author), Zhe Gao (Author), Qian Li (Author), Yun Hong (Author), Jiaying Wu (Author), Tingting Meng (Author), Hong Yuan (Author), Fuqiang Hu (Author)
• Formato: Libro
• Publicado: Elsevier, 2021-06-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Hepatitis B (HB) is a viral infectious disease that seriously endangers human health, and since there are no radical drugs to counter this, effective and safe therapies urgently need to be developed. HB virus (HBV) mainly infects hepatocytes (HCs), while the drugs are easily phagocytosed by Kupffer...