Development and Validation of an HPLC Method for the Analysis of Sirolimus in Drug Products

• Main Authors: Hadi Valizadeh (Author), Parvin Zakeri-Milani (Author), Shahram Emami (Author), Saeed Ghanbarzadeh (Author), Ziba Islambulchilar (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2012-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: The aim of this study was to develop a simple, rapid and sensitive reverse phase high performance liquid chromatography (RP-HPLC) method for quantification of sirolimus (SRL) in pharmaceutical dosage forms. Methods: The chromatographic system employs isocratic elution using a Knauer- C18, 5...