Curative Metatarsal Bone Surgery Combined with Intralesional Administration of Recombinant Human Epidermal Growth Factor in Diabetic Neuropathic Ulceration of the Forefoot: A Prospective, Open, Uncontrolled, Nonrandomized, Observational Study

• Main Authors: Aristides L. Garcia Herrera, MD, PhD (Author), Ridel de Jesús Febles Sanabria, MD, MS (Author), Liliana de los Ángeles Acosta Cabadilla, MD (Author), Miriam Moliner Cartaya (Author)
• Format: Book
• Published: Elsevier, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Curative surgery is performed for a foot with ulcers and loss of protective sensation to heal the wound and prevent amputation. Evidence supports that patients with diabetes have decreased concentrations of growth factors in their tissues, notably epidermal growth factor (EGF). Injecting...