Synthesis and Development of <i>N</i>-2,5-Dimethylphenylthioureido Acid Derivatives as Scaffolds for New Antimicrobial Candidates Targeting Multidrug-Resistant Gram-Positive Pathogens

• Main Authors: Povilas Kavaliauskas (Author), Birutė Grybaitė (Author), Rita Vaickelionienė (Author), Birutė Sapijanskaitė-Banevič (Author), Kazimieras Anusevičius (Author), Agnė Kriaučiūnaitė (Author), Gabrielė Smailienė (Author), Vidmantas Petraitis (Author), Rūta Petraitienė (Author), Ethan Naing (Author), Andrew Garcia (Author), Vytautas Mickevičius (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The growing antimicrobial resistance to last-line antimicrobials among Gram-positive pathogens remains a major healthcare emergency worldwide. Therefore, the search for new small molecules targeting multidrug-resistant pathogens remains of great importance. In this paper, we report the synthesis and...