Pembrolizumab Therapy Triggering an Exacerbation of Preexisting Autoimmune Disease

• Main Authors: Sneha D. Phadke DO (Author), Ramez Ghabour DO (Author), Brian L. Swick MD (Author), Andrea Swenson MD (Author), Mohammed Milhem MD (Author), Yousef Zakharia MD (Author)
• Format: Book
• Published: SAGE Publishing, 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Historically, metastatic melanoma was uniformly and rapidly lethal, and treatment options were limited. In recent years, however, checkpoint inhibitors have emerged as an accepted standard treatment for patients with advanced melanoma. In clinical trials, these agents have been largely well tolerate...