Biological treatments for pediatric Netherton syndrome

• Main Authors: Matteo Pontone (Author), Mattia Giovannini (Author), Cesare Filippeschi (Author), Teresa Oranges (Author), Fausto Andrea Pedaci (Author), Francesca Mori (Author), Simona Barni (Author), Federica Barbati (Author), Filippo Consonni (Author), Giuseppe Indolfi (Author), Lorenzo Lodi (Author), Chiara Azzari (Author), Silvia Ricci (Author), Alain Hovnanian (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Netherton syndrome (NS) is a rare and potentially life-threatening genetic skin disease responsible for skin inflammation and scaling, hair abnormalities and severe allergic manifestations. NS is caused by loss-of-function variants in Serine Peptidase Inhibitor Kazal-Type 5 (SPINK5), encoding the se...