Non-Antimicrobial Adjuvant Therapy Using Ticagrelor Reduced Biofilm-Related Staphylococcus aureus Prosthetic Joint Infection

• Main Authors: Narayan Pant (Author), Socorro Miranda-Hernandez (Author), Catherine Rush (Author), Jeffrey Warner (Author), Damon P. Eisen (Author)
• 格式: 图书
• 出版: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Background: Prosthetic joint infection (PJI), frequently caused by Staphylococcus aureus, leads to a significant arthroplasty failure rate. Biofilm is a crucial virulence factor of S. aureus that is intrinsic to the pathogenesis of PJI. Biofilm-related infections are recalcitrant to antibiotic treat...