Attenuation and efficacy of live-attenuated Rift Valley fever virus vaccine candidates in non-human primates.

• Main Authors: Darci R Smith (Author), Sara C Johnston (Author), Ashley Piper (Author), Miriam Botto (Author), Ginger Donnelly (Author), Joshua Shamblin (Author), César G Albariño (Author), Lisa E Hensley (Author), Connie Schmaljohn (Author), Stuart T Nichol (Author), Brian H Bird (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rift Valley fever virus (RVFV) is an important mosquito-borne veterinary and human pathogen that has caused large outbreaks of severe disease throughout Africa and the Arabian Peninsula. Currently, no licensed vaccine or therapeutics exists to treat this potentially deadly disease. The explosive nat...