Production of IL1-beta by ovarian cancer cells induces mesothelial cell beta1-integrin expression facilitating peritoneal dissemination

• Main Authors: Watanabe Takafumi (Author), Hashimoto Toshihiro (Author), Sugino Takashi (Author), Soeda Shu (Author), Nishiyama Hiroshi (Author), Morimura Yutaka (Author), Yamada Hidekazu (Author), Goodison Steve (Author), Fujimori Keiya (Author)
• Format: Book
• Published: BMC, 2012-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>A crucial step in the metastatic spread of ovarian cancer (OC) is the adhesion and implantation of tumor cells to the peritoneal mesothelium. In order to study this step in the cascade, we derived a pro-metastatic human ovarian carci...