Protective Effects of Kakkalide From Flos Puerariae on Ethanol-Induced Lethality and Hepatic Injury Are Dependent on Its Biotransformation by Human Intestinal Microflora

ABSTRACT: When kakkalide, which was isolated from Flos Puerariae, was incubated with human fecal bacteria, kakkalide was metabolized to irisolidone via kakkalidone. When kakkalide (250 mg/kg) was orally administered to rats, irisolidone, but not kakkalide, was detected in the blood. The mortality as...

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Main Authors: Yeo-Ok Han (Author), Myung Joo Han (Author), Sung-Hwan Park (Author), Dong-Hyun Kim (Author)
Format: Book
Published: Elsevier, 2003-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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