Dose-Dependent Solubility-Permeability Interplay for Poorly Soluble Drugs under Non-Sink Conditions

• मुख्य लेखकों: Kazuya Sugita (लेखक), Noriyuki Takata (लेखक), Etsuo Yonemochi (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

We investigated the solubility-permeability interplay using a solubilizer additive under non-sink conditions. Sodium lauryl sulfate (SLS) was used as a solubilizer additive. The solubility and permeability of two poorly soluble drugs at various doses, with or without SLS, were evaluated by flux meas...