The Potential Role of Matrix Metalloproteinases 8 and 9 and Myeloperoxidase in Predicting Outcomes of Bacterial Meningitis of Childhood

• Main Authors: Okko Savonius (Author), Irmeli Roine (Author), Saeed Alassiri (Author), Taina Tervahartiala (Author), Otto Helve (Author), Josefina Fernández (Author), Heikki Peltola (Author), Timo Sorsa (Author), Tuula Pelkonen (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Matrix metalloproteinases (MMPs) and myeloperoxidase (MPO) contribute to the inflammatory cascade in the cerebrospinal fluid (CSF) during bacterial meningitis. We determined levels of MPO, MMP-8, MMP-9, and tissue inhibitor of metalloproteinase- (TIMP-) 1 in the CSF of children with bact...