The Potential of iPS Cells in Synucleinopathy Research

• Main Authors: Leonhard Linta (Author), Marianne Stockmann (Author), Tobias M. Boeckers (Author), Alexander Kleger (Author), Stefan Liebau (Author)
• Format: Book
• Published: Hindawi Limited, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

α-synuclein is a protein involved in the pathogenesis of several so-called synucleinopathies including Parkinson's disease. A variety of models have been so far assessed. Human induced pluripotent stem cells provide a patient- and disease-specific model for in vitro studies, pharmacotoxicologic...