Pathophysiological mechanisms of statin‐associated myopathies: possible role of the ubiquitin‐proteasome system

• 主要な著者: Amirhossein Sahebkar (著者), Arrigo F.G. Cicero (著者), Paolo Di Giosia (著者), Irene Pomilio (著者), Cosimo Andrea Stamerra (著者), Paolo Giorgini (著者), Claudio Ferri (著者), Stephan vonHaehling (著者), Maciej Banach (著者), Tannaz Jamialahmadi (著者)
• フォーマット: 図書
• 出版事項: Wiley, 2020-10-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Background Statins are the cornerstone of pharmacotherapy for atherosclerotic cardiovascular disease. While these drugs are generally safe, treatment adherence is not optimal in a considerable proportion of patients because of the adverse effects on skeletal muscles in the forms of myopathy, myalgia...