Co-Amorphous Formation of Simvastatin-Ezetimibe: Enhanced Physical Stability, Bioavailability and Cholesterol-Lowering Effects in LDLr−/−Mice

• मुख्य लेखकों: Shamuha Bahetibieke (लेखक), Sakib M. Moinuddin (लेखक), Asiya Baiyisaiti (लेखक), Xiaoang Liu (लेखक), Jie Zhang (लेखक), Guomin Liu (लेखक), Qin Shi (लेखक), Ankang Peng (लेखक), Jun Tao (लेखक), Chang Di (लेखक), Ting Cai (लेखक), Rong Qi (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Hypercholesterolemia is one of the independent risk factors for the development of cardiovascular diseases such as atherosclerosis. The treatment of hypercholesterolemia is of great significance to reduce clinical cardiovascular events and patient mortality. Simvastatin (SIM) and ezetimibe (EZE) are...