Key role of MIF-related neuroinflammation in neurodegeneration and cognitive impairment in Alzheimer's disease

• Main Authors: Elham Nasiri (Author), Roman Sankowski (Author), Henriette Dietrich (Author), Aikaterini Oikonomidi (Author), Patricio T. Huerta (Author), Julius Popp (Author), Yousef Al-Abed (Author), Michael Bacher (Author)
• Format: Book
• Published: BMC, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Macrophage Migration Inhibitory Factor (MIF) is a potent proinflammatory cytokine that promotes the production of other immune mediators. MIF is produced by most cell types in the brain including microglia, astrocytes and neurons. Enhanced expression of MIF might contribute to th...