UFR2709, a Nicotinic Acetylcholine Receptor Antagonist, Decreases Ethanol Intake in Alcohol-Preferring Rats

• Main Authors: Gabriel Quiroz (Author), Ramón Sotomayor-Zárate (Author), Juan Pablo González-Gutierrez (Author), Franco Vizcarra (Author), Felipe Moraga (Author), Isabel Bermudez (Author), Miguel Reyes-Parada (Author), María Elena Quintanilla (Author), Diego Lagos (Author), Mario Rivera-Meza (Author), Patricio Iturriaga-Vásquez (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Brain nicotinic acetylcholine receptors (nAChRs), a heterogeneous family of pentameric acetylcholine-gated cation channels, have been suggested as molecular targets for the treatment of alcohol abuse and dependence. Here, we examined the effect of the competitive nAChR antagonist UFR2709 on the alco...