Our Evolving Understanding of the Mechanism of Quinolones

• Main Authors: Arnaud Gutierrez (Author), Jonathan M. Stokes (Author), Ivan Matic (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2018-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The maintenance of DNA supercoiling is essential for the proper regulation of a plethora of biological processes. As a consequence of this mode of regulation, ahead of the replication fork, DNA replication machinery is prone to introducing supercoiled regions into the DNA double helix. Resolution of...