Numaswitch, a biochemical platform for the efficient production of disulfide-rich pepteins

• Autores principales: Bach-Ngan Nguyen (Autor), Florian Tieves (Autor), Florian G. Neusius (Autor), Hansjörg Götzke (Autor), Lutz Schmitt (Autor), Christian Schwarz (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The application of long-chained peptides (+30 aa) and relatively short proteins (<300 aa) has experienced an increasing interest in recent years. However, a reliable production platform is still missing since manufacturing is challenged by inherent problems such as mis-folding, aggregation, and l...