A Subgroup of Latently Mycobacterium tuberculosis Infected Individuals Is Characterized by Consistently Elevated IgA Responses to Several Mycobacterial Antigens

• Main Authors: Ralf Baumann (Author), Susanne Kaempfer (Author), Novel N. Chegou (Author), Wulf Oehlmann (Author), Ralf Spallek (Author), André G. Loxton (Author), Paul D. van Helden (Author), Gillian F. Black (Author), Mahavir Singh (Author), Gerhard Walzl (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Elevated antibody responses to Mycobacterium tuberculosis antigens in individuals with latent infection (LTBI) have previously been linked to an increased risk for progression to active disease. Studies in the field focussed mainly on IgG antibodies. In the present study, IgA and/or IgG responses to...