Effect of xanthan gum-based food thickeners on the dissolution profile of fluoroquinolones oral formulations

• Hauptverfasser: Nobuyuki Takahashi (Verfasst von), Yoshiaki Fujita (Verfasst von), Nanako Takahashi (Verfasst von), Akihiro Nakamura (Verfasst von), Tsutomu Harada (Verfasst von)
• Format: Buch
• Veröffentlicht: BMC, 2020-11-01T00:00:00Z.
• Schlagworte: article
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Abstract Background Xanthan gum-based food thickeners (XG-FTs) are often ingested by patients with dysphagia to prevent aspiration during drug treatment. Reportedly, XG-FTs affect tablet disintegration, drug dissolution rates, and reduce the efficacy of postprandial antihyperglycemic agents. The abs...