Continuous Infusion of High Doses of Cefepime in Intensive Care Unit: Assessment of Steady-State Plasma Level and Incidence on Neurotoxicity

• Glavni autori: Vanessa Jean-Michel (Autor), Corentin Homey (Autor), Patrick Devos (Autor), Pierre-Yves Delannoy (Autor), Nicolas Boussekey (Autor), Thomas Caulier (Autor), Olivier Leroy (Autor), Hugues Georges (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2022-12-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Continuous infusion (CI) with high doses of cefepime is recommended in the empirical antimicrobial regimen of critically ill patients with suspected Gram-negative sepsis. This study aimed to determine factors associated with cefepime overdosing and the incidence of cefepime-induced neurotoxicity (CI...