CRISPR-Cas13a Inhibits HIV-1 Infection

• Автори: Lijuan Yin (Автор), Fei Zhao (Автор), Hong Sun (Автор), Zhen Wang (Автор), Yu Huang (Автор), Weijun Zhu (Автор), Fengwen Xu (Автор), Shan Mei (Автор), Xiaoman Liu (Автор), Di Zhang (Автор), Liang Wei (Автор), Shan Cen (Автор), Siqi Hu (Автор), Chen Liang (Автор), Fei Guo (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2020-09-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

CRISPR-Cas provides bacteria and archaea with immunity against invading phages and foreign plasmid DNA and has been successfully adapted for gene editing in a variety of species. The class 2 type VI CRISPR-Cas effector Cas13a targets and cleaves RNA, providing protection against RNA phages. Here we...