Protection against Lipopolysaccharide-Induced Endotoxemia by Terrein Is Mediated by Blocking Interleukin-1β and Interleukin-6 Production

• Main Authors: Yeo Dae Yoon (Author), Myeong Youl Lee (Author), Byeong Jo Choi (Author), Chang Woo Lee (Author), Hyunju Lee (Author), Joo-Hee Kwon (Author), Jeong-Wook Yang (Author), Jong Soon Kang (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Terrein is a fungal metabolite and has been known to exert anti-melanogenesis, anti-cancer, and anti-bacterial activities. However, its role in endotoxemia has never been investigated until now. In the present study, we examined the effect of terrein on lipopolysaccharide (LPS)-induced endotoxemia i...