CD44 deficiency represses neuroinflammation and rescues dopaminergic neurons in a mouse model of Parkinson's disease

• Main Authors: Yuejun Wang (Author), Li Li (Author), Yuting Wu (Author), Shouping Zhang (Author), Qianqian Ju (Author), Yinuo Yang (Author), Yan Jin (Author), Hui Shi (Author), Cheng Sun (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

CD44 is a transmembrane protein that transduces extracellular stimuli to immune response. Neuroinflammation is a causative factor in neurodegenerative diseases, such as Parkinson's disease (PD). Owing to its role in inflammation, this study investigated whether CD44 is involved in the pathologi...