Riluzole Does Not Affect Hippocampal Synaptic Plasticity and Spatial Memory, Which Are Impaired by Diazepam in Rats

• Main Authors: Sachie Sasaki-Hamada (Author), Hiroaki Sacai (Author), Azusa Sugiyama (Author), Takahiro Iijima (Author), Akiyoshi Saitoh (Author), Masatoshi Inagaki (Author), Mitsuhiko Yamada (Author), Jun-Ichiro Oka (Author)
• Format: Book
• Published: Elsevier, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We have previously demonstrated that riluzole has anxiolytic-like effects in rats, without affecting spontaneous alternation performance in the Y-maze test. However, the effects of riluzole on hippocampal synaptic plasticity were still unclear. In this study, we showed that bath application of riluz...