Mitotane Nanocarriers for the Treatment of Adrenocortical Carcinoma: Evaluation of Albumin-Stabilized Nanoparticles and Liposomes in a Preclinical In Vitro Study with 3D Spheroids

Adrenocortical carcinoma (ACC) is a heterogeneous malignancy related to poor prognosis and limited treatment options. The orphan drug mitotane (MT) is still a cornerstone in ACC therapy, however, its application is characterized by low aqueous solubility, poor bioavailability, and unfavorable pharma...

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Main Authors: Carolin Langer (Author), Monika Köll-Weber (Author), Martin Holzer (Author), Constanze Hantel (Author), Regine Süss (Author)
Format: Book
Published: MDPI AG, 2022-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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