Rev-Erb co-regulates muscle regeneration via tethered interaction with the NF-Y cistrome

• Main Authors: Ryan D. Welch (Author), Chun Guo (Author), Monideepa Sengupta (Author), Katherine J. Carpenter (Author), Natalie A. Stephens (Author), Stacy A. Arnett (Author), Marvin J. Meyers (Author), Lauren M. Sparks (Author), Steven R. Smith (Author), Jinsong Zhang (Author), Thomas P. Burris (Author), Colin A. Flaveny (Author)
• Format: Book
• Published: Elsevier, 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The loss of skeletal muscle mass and strength are a central feature of traumatic injury and degenerative myopathies. Unfortunately, pharmacological interventions typically fail to stem the long-term decline in quality of life. Reduced Rev-Erb-mediated gene suppression in cultured C2C12 my...