Simvastatin enhances irinotecan-induced apoptosis in prostate cancer via inhibition of MCL-1

• Hauptverfasser: Mohammad A.Y. Alqudah (Verfasst von), Hebah T. Mansour (Verfasst von), Nizar Mhaidat (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2018-02-01T00:00:00Z.
• Schlagworte: article
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Prostate cancer is one of the most common malignant tumors around the world. Hyperlipidemia is considered as one of the most important risk factors for the development of prostate cancer. Simvastatin is widely used for the treatment of hyperlipidemia and was previously shown to induce apoptosis in s...