Co-expression and clinical utility of AR-FL and AR splice variants AR-V3, AR-V7 and AR-V9 in prostate cancer

• Main Authors: Neele Wüstmann (Author), Konstantin Seitzer (Author), Verena Humberg (Author), Julia Vieler (Author), Norbert Grundmann (Author), Julie Steinestel (Author), Dorothee Tiedje (Author), Stefan Duensing (Author), Laura-Maria Krabbe (Author), Martin Bögemann (Author), Andres Jan Schrader (Author), Christof Bernemann (Author), Katrin Schlack (Author)
• Formato: Livro
• Publicado em: BMC, 2023-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Androgen receptor (AR) splice variants (AR-Vs) have been discussed as a biomarker in prostate cancer (PC). However, some reports question the predictive property of AR-Vs. From a mechanistic perspective, the connection between AR full length (AR-FL) and AR-Vs is not fully underst...