TNF-α Downregulation Modifies Insulin Receptor Substrate 1 (IRS-1) in Metabolic Signaling of Diabetic Insulin-Resistant Hepatocytes

One of the major mechanisms of hyperglycemia in type 2 diabetes is insulin resistance (IR) which can induce free fatty acids like palmitate. In hepatic cell, as an insulin target tissue, insulin resistance can be stimulated by inflammatory cytokine TNF-α. The interaction of intracellular TNF-α signa...

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Main Authors: Iraj Alipourfard (Author), Nelly Datukishvili (Author), Davit Mikeladze (Author)
Format: Book
Published: Hindawi Limited, 2019-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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