Efficient Delivery of Curcumin by Alginate Oligosaccharide Coated Aminated Mesoporous Silica Nanoparticles and In Vitro Anticancer Activity against Colon Cancer Cells

• Main Authors: Chennan Liu (Author), Fangyuan Jiang (Author), Zifeng Xing (Author), Lihong Fan (Author), Yuan Li (Author), Shaoning Wang (Author), Junhong Ling (Author), Xiao-Kun Ouyang (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We designed and synthesized aminated mesoporous silica (MSN-NH₂), and functionally grafted alginate oligosaccharides (AOS) on its surface to get MSN-NH₂-AOS nanoparticles as a delivery vehicle for the fat-soluble model drug curcumin (Cur). Dynamic light...