Hinokiflavone induces apoptosis, cell cycle arrest and autophagy in chronic myeloid leukemia cells through MAPK/NF-κB signaling pathway

• Main Authors: Xiang Qin (Author), Xi Chen (Author), Ling Guo (Author), Jing Liu (Author), You Yang (Author), Yan Zeng (Author), Cheng Li (Author), Wenjun Liu (Author), Wenzhe Ma (Author)
• Format: Book
• Published: BMC, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Chronic myeloid leukemia (CML) is a myeloproliferative tumor originating from hematopoietic stem cells, and resistance to tyrosine kinase inhibitors (TKI) has become a major cause of treatment failure. Alternative drug therapy is one of the important ways to overcome TKI resistan...