Nontargeted metabolomics to characterize the effects of isotretinoin on skin metabolism in rabbit with acne

Background: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit. This study aimed to explore the pathogenesis of acne and the therapeutic mechanism of isotretinoin from the metabolic perspective in coal tar-induced acne in rabbits.Methods: Ultra-high performance liquid chromato...

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Main Authors: Xiao-Li (Author), Deng Zhang (Author), Xiu-Ping Wang (Author), Si-Min Yu (Author), Zhen Xiao (Author), Wei Li (Author), Chun-Ming Li (Author)
Format: Book
Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
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