Growth Arrest-Specific 6 Enhances the Suppressive Function of CD4+CD25+ Regulatory T Cells Mainly through Axl Receptor

• Hoofdauteurs: Guang-ju Zhao (Auteur), Jia-yi Zheng (Auteur), Jia-lan Bian (Auteur), Long-wang Chen (Auteur), Ning Dong (Auteur), Yan Yu (Auteur), Guang-liang Hong (Auteur), Arvine Chandoo (Auteur), Yong-Ming Yao (Auteur), Zhong-qiu Lu (Auteur)
• Formaat: Boek
• Gepubliceerd in: Hindawi Limited, 2017-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Background. Growth arrest-specific (Gas) 6 is one of the endogenous ligands of TAM receptors (Tyro3, Axl, and Mertk), and its role as an immune modulator has been recently emphasized. Naturally occurring CD4+CD25+ regulatory T cells (Tregs) are essential for the active suppression of autoimmunity. T...