Positive Modulatory Interactions of NMDA Receptor GluN1/2B Ligand Binding Domains Attenuate Antagonists Activity

• Үндсэн зохиолчид: Douglas Bledsoe (Зохиогч), Ceyhun Tamer (Зохиогч), Ivana Mesic (Зохиогч), Christian Madry (Зохиогч), Bradley G. Klein (Зохиогч), Bodo Laube (Зохиогч), Blaise M. Costa (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2017-05-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

N-methyl D-aspartate receptors (NMDAR) play crucial role in normal brain function and pathogenesis of neurodegenerative and psychiatric disorders. Functional tetra-heteromeric NMDAR contains two obligatory GluN1 subunits and two identical or different non-GluN1 subunits that include six different ge...