Positive Modulatory Interactions of NMDA Receptor GluN1/2B Ligand Binding Domains Attenuate Antagonists Activity

• Główni autorzy: Douglas Bledsoe (Autor), Ceyhun Tamer (Autor), Ivana Mesic (Autor), Christian Madry (Autor), Bradley G. Klein (Autor), Bodo Laube (Autor), Blaise M. Costa (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2017-05-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

N-methyl D-aspartate receptors (NMDAR) play crucial role in normal brain function and pathogenesis of neurodegenerative and psychiatric disorders. Functional tetra-heteromeric NMDAR contains two obligatory GluN1 subunits and two identical or different non-GluN1 subunits that include six different ge...