Intranasal Immunization with Zika Virus Envelope Domain III-Flagellin Fusion Protein Elicits Systemic and Mucosal Immune Responses and Protection against Subcutaneous and Intravaginal Virus Challenges

• मुख्य लेखकों: Chi-Hsun Chen (लेखक), Chung-Chu Chen (लेखक), Wei-Bo Wang (लेखक), Vania Lionel (लेखक), Chia-Chyi Liu (लेखक), Li-Min Huang (लेखक), Suh-Chin Wu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Zika virus (ZIKV) infections in humans are mainly transmitted by the mosquito vectors, but human-to-human sexual transmission is also another important route. Developing a ZIKV mucosal vaccine that can elicit both systemic and mucosal immune responses is of particular interest. In this study, we con...