Hyaluronic Acid-Functionalized Mesoporous Silica Nanoparticles Loading Simvastatin for Targeted Therapy of Atherosclerosis

• Main Authors: Kechen Song (Author), Zhuang Tang (Author), Zhiling Song (Author), Shiyu Meng (Author), Xiaoxue Yang (Author), Hui Guo (Author), Yizhun Zhu (Author), Xiaolin Wang (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Atherosclerosis (AS) constitutes a major threat to human health, yet most current therapeutics are hindered in achieving desirable clinical outcomes by low bioavailability or serious side effects. Herein, we constructed an enzyme-responsive and macrophage-targeting drug delivery system (SIM@HA-MSN)...