Dickkopf Proteins and Their Role in Cancer: A Family of Wnt Antagonists with a Dual Role

• Main Authors: Irina Giralt (Author), Gabriel Gallo-Oller (Author), Natalia Navarro (Author), Patricia Zarzosa (Author), Guillem Pons (Author), Ainara Magdaleno (Author), Miguel F. Segura (Author), José Sánchez de Toledo (Author), Lucas Moreno (Author), Soledad Gallego (Author), Josep Roma (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The Wnt signaling pathway regulates crucial aspects such as cell fate determination, cell polarity and organogenesis during embryonic development. Wnt pathway deregulation is a hallmark of several cancers such as lung, gastric and liver cancer, and has been reported to be altered in others. Despite...